Skin and Bones by Thorne Smith

A photographer’s freak accident in the dark room produces a chemical concoction causing him (and his dog) to randomly switch back and forth between normal and X-ray (skeleton) versions of themselves. Predictably, much drinking and cavorting ensues, as he finds people able to see beyond his appearance and appreciate him for who he is, while inadvertently terrifying those who can not. Unusually, his wife Lorna is an attractive personality.